Skip to main content

Kleos Health

We Know Healthcare.™

Kleos Connect

Exosomes vs PDRN: Which Advanced Topical Technology Fits Your Clinic?

Exosomes and PDRN are the two most requested advanced skincare technologies in aesthetic clinics. They are often mentioned together, but they are different ingredients with different stories. Here is how they compare, and how to decide what your clinic should offer.

At a glance

  • What it is. Topical exosomes: Nano-sized extracellular vesicles, measured in billions per treatment. Topical PDRN: A refined fraction of salmon DNA.
  • Where it comes from. Topical exosomes: Different sources; ask your supplier, as source matters for compliance. Topical PDRN: Salmon.
  • Cosmetic positioning. Topical exosomes: Visibly calmer, radiant-looking skin after treatment; scalp and hair care. Topical PDRN: Hydrated, smoother, more even-looking skin; the K-beauty story.
  • Patient awareness. Topical exosomes: High, driven by social media and celebrity mentions. Topical PDRN: High, driven by Korean skincare.
  • Typical use in clinic. Topical exosomes: Finishing step after microneedling, laser, RF, peels; scalp treatments. Topical PDRN: Finishing step after facials, peels, microneedling, laser.
  • Storage. Topical exosomes: Often freeze-dried and room-temperature stable. Topical PDRN: Usually liquid; follow the label.
  • What to verify. Topical exosomes: Source, count per treatment and how it was measured. Topical PDRN: Concentration and purity.

Choose exosomes when

  • Your clinic is built around microneedling, RF microneedling or laser and you want a premium finishing step.
  • You offer scalp and hair-care treatments.
  • Your patients ask for exosomes by name.

Choose PDRN when

  • Your patients are drawn to Korean skincare and the salmon DNA story.
  • Your menu leans toward facials, peels and skin-quality treatments.

Offer both when

Many clinics offer both, as separate premium add-ons or layered within one signature protocol. Offering both lets your team match the technology to each patient’s goals, and gives returning patients something new to try.

How Kleos Health helps

Kleos Health supplies both Advanced Exosome Technology and Advanced PDRN Technology as topical cosmetics, and designs protocols that combine them around your devices and menu. New to PDRN? Start with What Is PDRN?

Frequently asked questions

Is PDRN better than exosomes?
Neither is better for every clinic. Exosomes suit device-led clinics and scalp care; PDRN suits facial and skin-quality menus and the Korean skincare story. Many clinics offer both.

Can exosomes and PDRN be used together?
Yes. Many clinics layer them within one protocol or offer them as separate premium options, following each product’s label.

Which is easier to explain to patients?
Both are easy: exosomes as advanced skincare for calmer, radiant-looking skin after treatment; PDRN as the salmon DNA secret of Korean aesthetics.

Where can clinics buy exosomes and PDRN in Canada and the US?
Kleos Health supplies both to licensed clinics across Canada and the United States.

Kleos Connect.

Korean Skincare in the Clinic: Bringing PDRN, Exosomes and K-Beauty Protocols to Your Practice

Why Korean skincare technologies such as PDRN and topical exosomes are in demand in Canadian and US clinics, and how to build K-beauty protocols into your menu.

Read More

Post-Procedure Skincare for Clinics: The Exosome Sheet Mask and Barrier Cream

How clinics finish microneedling, laser and peel appointments with an exosome sheet mask and barrier cream, for skin that looks calm, hydrated and radiant.

Read More

Exosomes vs PDRN: Which Advanced Topical Technology Fits Your Clinic?

A side-by-side comparison of topical exosome and PDRN (salmon DNA) skincare for clinics: what each is, how patients respond to each, and when to offer one, the other or both.

Read More